By Health Center: Blood%20
FDA Approves New Indication for Tasigna (nilotinib)
The U.S. Food and Drug Administration today approved a new indication for
Tasigna (nilotinib) for the treatment of a rare blood cancer when it is first diagnosed. The cancer, called Philadelphia chromosome positive chronic phase chronic myeloid leukemia (Ph+ CP-CML), is a slowly progressing blood and bone marrow disease linked to a genetic abnormality.
FDA Approves Rituxan (Rituximab) to Treat Chronic Lymphocytic Leukemia
The U.S. Food and Drug Administration today approved Rituxan (rituximab) to treat certain patients with chronic lymphocytic leukemia (CLL), a slowly progressing blood and bone marrow cancer. Rituxan, an anti-cancer drug, is intended for patients with CLL who are beginning chemotherapy for the first time and for those who have not responded to other cancer drugs for CLL. Rituxan is administered with two other chemotherapy drugs, fludarabine and cyclophosphamide.
Lenalidomide (Revlimid) Extends Disease-Free Survival in Multiple Myeloma
Initial results from a large, randomized clinical trial for patients with multiple myeloma, a cancer of the blood and bone marrow, showed that patients who received the oral drug lenalidomide (Revlimid, also known as CC-5013) following a blood stem cell transplant had their cancer kept in check longer than patients who received a placebo. The clinical trial, for patients ages 18 to 70, was sponsored by the National Cancer Institute (NCI), and conducted by a network of researchers led by the C...
Risk of Pancreatic Cancer Linked to Variation in Gene that Determines Blood Type
Common variants of the gene that determines human blood type are associated with an increased risk of pancreatic cancer, according to a study by scientists at the National Cancer Institute (NCI), part of the National Institutes of Health, and colleagues from many universities and research institutions. The study, published online Aug. 2, 2009, in Nature Genetics, is consistent with an observation first made more than 50 years ago.
The NHLBI Halts Study of Concentrated Saline for Patients with Shock Due to Lack of Survival Benefit
The National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health has stopped a clinical trial studying the benefits and safety of administering a highly concentrated form of saline solution in the ambulance (before hospital arrival) to trauma patients suffering from shock due to severe bleeding. The trial was stopped because patients who received the concentrated saline solutions were no more likely to survive than those who received a normal saline solution. A paral...